Dinotefuran

Applications detail

Highly systemic furanicotinyl insecticide for crop and pest control.

Applications

Introduction
Characteristics
Field Performance

Dinotefuran is a new furanicotinyl insecticide which represents the third generation of neonicotinoid group. Dinotefuran, which was developed by Mitsui Chemicals, Inc., was registered in Japan April 24, 2002 and the registration has been submitted to the Environment Protection Agency (EPA) in the USA. Dinotefuran was granted Organophosphorus Alternative and Reduced Risk Status by the EPA.

Physical & Chemicals Properties

Code:	MTI-446
Common Name:	Dinotefuran (ISO name)
Chemical Name:	(RS)-1-methyl-2-nitro-3-(tetrahydro-3-furylmethyl) guanidine
Chemical Structure:
Melting Point:	107.5° C
Water Solubility:	39.83 g/L

Acute Toxicity for Mammalian (Technical)

Oral (Rat, Mouse)	LD₅₀	≥2,000 mg/kg
Dermal (Rat)	LD₅₀	>2,000 mg/kg

Avian & Aquatic Toxicity (Technical)

Japanese quail	LD₅₀	≥2,000 mg/kg
Mallard duck	LD₅₀	>997.9 mg/kg/day
Carp	LD₅₀ (96hr)	>1,000 ppm
Daphnia	LD₅₀ (48hr)	>1,000 ppm

Skin Irritation (Technical)

Slightly Irritating

Long Term Health Effects (Technical)

Dinotefuran is not a mutagen, neurotoxin or reproductive toxin.

Ecological Effect

Dinotefuran is highly toxic to honeybees and silkworms.

Hydrolysis	Stable
Photolysis on Soil	46 days
Aerobic Soil Metabolism	52 days
Field Dissipation	22 to 68 days

Dinotefuran acts through contact and ingestion and results in the cessation of feeding within several hours of contact and death shortly after. Dinotefuran does not inhibit cholinesterase or interfere with sodium channels. Therefore, its mode of action is different from those of organophosphate, carbamate, and pyrethroid compounds. It appears that Dinotefuran acts as an agonist of insect nicotinic acetylcholine receptors, but it is postulated that Dinotefuran affects the nicotinic acetylcholine binding in a mode that differs from other neonicotinoid insecticides. It is reported that Dinotefuran was highly active on a certain silverleaf whitefly strain which developed resistance against imidacloprid.

The information contained in this website is, to the best of our knowledge, accurate and reliable, but all suggestions are made without warranty, either express or implied. The values relevant to properties or the like of the product stated herein were obtained using field test specimens prepared at official organizations in some countries and are not assumed to be identical to values obtained on the finished product manufactured by our customers and on our finished product tested by our customers in a different condition. Nothing herein shall be construed as permission or as recommendation for uses which infringe valid patents or as extending a license under valid patents. Because the conditions and methods of use on the part of our customers are beyond our control, Mitsui Chemicals, Inc. disclaims any liability incurred in connection with the use of our products.

Dinotefuran Precautions and Safety (old)

PRECAUTIONS

Avoid contact with eyes, skin or clothing. When measuring and mixing the product, wear protective garment, waterproof gloves, protective mask and goggles, rubber boots, apron and hat. At spraying, wear protective garment, shoes and hat.
Wash exposed skin thoroughly with soap and water after handling and application.
Do not apply in a fish farm or in shrimp, prawn or crab pond/ nursery.
This product is toxic to bees exposed to direct treatment or residues on blooming crops or weeds. Do not apply this product or allow it to drift to blooming crops or weeds if bees are visiting the treatment area.
This product is toxic to silkworms exposed to direct treatment or residues on mulberry leaves. Do not apply this product or allow it to drift to mulberry trees.

STORAGE AND DISPOSAL

Store in a closed, cool, dry place and away from fire and sunshine.
Store in original container in safe place and away from reach of children.
Burn or bury empty containers in an isolated area according to local rules and away from sources of water. Do not reuse.

FIRST AID

SKIN CONTACT: Immediately wash with soap and water.
EYE SPLASHES: Flush eyes immediately with steady running water for at least 15 minutes. Get medical attention immediately.
IF INHALED: Remove victim from area of exposure and move to fresh air. Get medical attention.
IF SWALLOWED: DO NOT induce vomiting. Give one or two glasses of water and GET MEDICAL ATTENTION IMMEDIATELY. Never give anything by mouth to an unconscious person.

ALWAYS FOLLOW THE LABEL INSTRUCTIONS BEFORE USE